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Vaccine Delivery and Immune Response Basics

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Vaccine Delivery Technology

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2183))

Abstract

In this opening chapter, we outline the basics of vaccine delivery and subsequent immune reactivity. Vaccine delivery is an augmentation to immunization more generally in that a delivery reagent is harnessed to improve administration of the key ingredient (i.e., the antigen) needed to provoke an immune response. In this chapter, we discuss the evolution of vaccine design and how such efforts evolved into targeted administration/delivery of key antigens. We then provide overview descriptions of vaccine immune responses and methods for assessment. More generally, the chapter sets the tone for the remainder of this book, which will focus upon each step of the vaccine process with a special emphasis on how vaccine delivery contributes to overall health outcomes.

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Author information

Authors and Affiliations

  1. Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Andrew Hill & Blaine A. Pfeifer

  2. Department of Chemical and Biological Engineering, The State University of New York at Buffalo, Buffalo, NY, USA

    Marie Beitelshees

Authors
  1. Andrew Hill
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  2. Marie Beitelshees
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  3. Blaine A. Pfeifer
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Corresponding author

Correspondence to Blaine A. Pfeifer .

Editor information

Editors and Affiliations

  1. Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Blaine A. Pfeifer

  2. Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA

    Andrew Hill

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Hill, A., Beitelshees, M., Pfeifer, B.A. (2021). Vaccine Delivery and Immune Response Basics. In: Pfeifer, B.A., Hill, A. (eds) Vaccine Delivery Technology. Methods in Molecular Biology, vol 2183. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0795-4_1

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  • DOI: https://doi.org/10.1007/978-1-0716-0795-4_1

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0794-7

  • Online ISBN: 978-1-0716-0795-4

  • eBook Packages: Springer Protocols

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