Skip to main content

Nanoparticle Characterization Through Nano-Impact Electrochemistry: Tools and Methodology Development

Part of the Methods in Molecular Biology book series (MIMB,volume 2118)

Abstract

The field of nanomaterials has been expanding rapidly into many diverse applications within the last 20 years. With this growth, there is a significant need for new method development for the detection and characterization of nanomaterials. Understanding the physical properties of nanoscale entities and their associated reaction kinetics is crucial for monitoring their effect on environmental and human health, and in their use for practical applications. Nano-impact electrochemistry is a novel development in the field of fundamental electrochemistry that provides an ultrasensitive method for analyzing physical and redox properties of nanomaterials and their derivatives. This protocol focuses on the tools required for characterizing silver nanoparticles (AgNPs) by nano-impact electrochemistry, the preparation of microelectrodes and the methodology needed for measurement of the AgNP redox activity. The fabrication of cylindrical carbon fiber as well as gold and platinum microwire electrodes is described in detail. The analysis of nano-impact electrochemistry for the characterization of redox active entities is also outlined with examples of applications.

Key words

This is a preview of subscription content, log in via an institution.

Buying options

Protocol
USD   49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Springer Nature is developing a new tool to find and evaluate Protocols. Learn more

References

  1. Zhou Y-G, Rees NV, Compton RG (2011) The electrochemical detection and characterization of silver nanoparticles in aqueous solution. Angew Chem 123:4305–4307

    Article  Google Scholar 

  2. Xiao X, Fan F-RF, Zhou J et al (2008) Current transients in single nanoparticle collision events. J Am Chem Soc 130:16669–16677

    Article  CAS  Google Scholar 

  3. Andreescu D, Kirk KA, Narouei FH et al (2018) Electroanalytic aspects of single-entity collision methods for bioanalytical and environmental applications. ChemElectroChem 5:2920–2936

    Article  CAS  Google Scholar 

  4. Oja SM, Robinson DA, Vitti NJ et al (2016) Observation of multipeak collision behavior during the electro-oxidation of single Ag nanoparticles. J Am Chem Soc 139:708–718

    Article  Google Scholar 

  5. Qiu D, Wang S, Zheng Y et al (2013) One at a time: counting single-nanoparticle/electrode collisions for accurate particle sizing by overcoming the instability of gold nanoparticles under electrolytic conditions. Nanotechnology 24:505707

    Article  Google Scholar 

  6. Sardesai NP, Andreescu D, Andreescu S (2013) Electroanalytical evaluation of antioxidant activity of cerium oxide nanoparticles by nanoparticle collisions at microelectrodes. J Am Chem Soc 135:16770–16773

    Article  CAS  Google Scholar 

  7. Kwon SJ, Zhou H, Fan F-RF et al (2011) Stochastic electrochemistry with electrocatalytic nanoparticles at inert ultramicroelectrodes—theory and experiments. Phys Chem Chem Phys 13:5394–5402

    Article  CAS  Google Scholar 

  8. Karimi A, Hayat A, Andreescu S (2017) Biomolecular detection at ssdna-conjugated nanoparticles by nano-impact electrochemistry. Biosens Bioelectron 87:501–507

    Article  CAS  Google Scholar 

  9. Anahita K, Kirk KA, Silvana A (2017) Electrochemical investigation of pH-dependent activity of polyethylenimine-capped silver nanoparticles. ChemElectroChem 4:2801–2806

    Article  Google Scholar 

  10. Hao R, Zhang B (2016) Observing electrochemical dealloying by single-nanoparticle collision. Anal Chem 88:8728–8734

    Article  CAS  Google Scholar 

  11. Cheng W, Zhou XF, Compton RG (2013) Electrochemical sizing of organic nanoparticles. Angew Chem 125:13218–13220

    Article  Google Scholar 

  12. Lim CS, Tan SM, Ze S et al (2015) Impact electrochemistry of layered transition metal dichalcogenides. ACS Nano 9:8474–8483

    Article  CAS  Google Scholar 

  13. Robinson DA, Yoo JJ, Castaneda AD et al (2015) Increasing the collision rate of particle impact electroanalysis with magnetically guided Pt-decorated iron oxide nanoparticles. ACS Nano 9:7583–7595

    Article  CAS  Google Scholar 

  14. Cheng W, Compton RG (2014) Investigation of single-drug-encapsulating liposomes using the nano-impact method. Angew Chem Int Ed 53:13928–13930

    Article  CAS  Google Scholar 

  15. Dick JE, Hilterbrand AT, Boika A et al (2015) Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring. Proc Natl Acad Sci U S A 112:5303–5308

    Article  CAS  Google Scholar 

  16. Castaneda AD, Robinson DA, Stevenson KJ et al (2016) Electrocatalytic amplification of DNA-modified nanoparticle collisions via enzymatic digestion. Chem Sci 7:6450–6457

    Article  CAS  Google Scholar 

  17. Robinson DA, Liu Y, Edwards MA et al (2017) Collision dynamics during the electrooxidation of individual silver nanoparticles. J Am Chem Soc 139:16923–16931

    Article  CAS  Google Scholar 

Download references

Acknowledgments

The manuscript was edited by Enrico Ferrari and Mikhail Soloviev. This material is based upon work supported by the National Science Foundation under Grant 1610281. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Silvana Andreescu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Science+Business Media, LLC, part of Springer Nature

About this protocol

Check for updates. Verify currency and authenticity via CrossMark

Cite this protocol

Kirk, K.A., Luitel, T., Narouei, F.H., Andreescu, S. (2020). Nanoparticle Characterization Through Nano-Impact Electrochemistry: Tools and Methodology Development. In: Ferrari, E., Soloviev, M. (eds) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, vol 2118. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0319-2_24

Download citation

  • DOI: https://doi.org/10.1007/978-1-0716-0319-2_24

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0318-5

  • Online ISBN: 978-1-0716-0319-2

  • eBook Packages: Springer Protocols

Publish with us

Policies and ethics