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Positron Emission Tomography-Based Molecular Imaging

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Animal Models of Brain Tumors

Part of the book series: Neuromethods ((NM,volume 77))

Abstract

Positron emission tomography (PET) is a nuclear imaging technique that can yield information on the temporal and spatial dynamics of various disease-specific or drug-induced biological alterations in intact tissues and living organisms. In this chapter we elucidate how this information can be generated and used in brain tumor animal models to give insight into tumor characteristics and guide anticancer treatment.

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Acknowledgments

Our work is supported in part by the 6th Framework EU grants EMIL (LSHC-CT-2004-503569), DiMI (LSHB-CT-2005-512146) and CliniGene NoE (LSHB-CT-2006-018933), the Innovative Medicines Initiative (IMI) grant QuIC-ConCePT (Quantitative Imaging in Cancer: Connecting Cellular Processes with Therapy), the European Strategy Forum on Research Infrastructures (ESFRI) project Euro-BioImaging and by the Bundesministerium für Bildung und Forschung (MoBiMed 01EZ0811). We thank Nina Gerigk (EIMI, Münster) for the design of Fig. 1.

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Authors and Affiliations

  1. European Institute for Molecular Imaging (EIMI), Westfälische Wilhelms-Universität Münster (WWU), Münster, Germany

    Yannic Waerzeggers, Thomas Viel, Sonja Schäfers, Andreas Faust & Klaus Schäfers

  2. Department of Nuclear Medicine, Westfälische Wilhelms-Universität Münster (WWU), Münster, Germany

    Stefan Wagner & Burkhard Riemann

  3. Department of Nuclear Medicine, Interdisciplinary Center for Clinical Research (IZKF), Westfälische Wilhelms-Universität Münster (WWU), Münster, Germany

    Klaus Kopka

  4. Department of Nuclear Medicine, European Institute for Molecular Imaging (EIMI), Westfälische Wilhelms-Universität Münster (WWU), Münster, Germany

    Otmar Schober

  5. Department of Nuclear Medicine, Interdisciplinary Center for Clinical Research (IZKF), European Institute for Molecular Imaging (EIMI), Westfälische Wilhelms-Universität Münster (WWU), Münster, Germany

    Andreas H. Jacobs

Authors
  1. Yannic Waerzeggers
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  2. Thomas Viel
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  4. Stefan Wagner
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  5. Andreas Faust
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  6. Burkhard Riemann
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  7. Klaus Kopka
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  8. Otmar Schober
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  9. Klaus Schäfers
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  10. Andreas H. Jacobs
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Corresponding author

Correspondence to Andreas H. Jacobs .

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Editors and Affiliations

  1. Instituto Cajal, Molecular, Cellular & Developmental Neur, CSIC, Avda. Doctor Arce 37, Madrid, 28002, Spain

    Ricardo Martínez Murillo

  2. de la Rioja (CIBIR), Oncology Area, Centro de Investigación Biomédica, C/ Piqueras 98, Logroño, 26006, Spain

    Alfredo Martínez

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© 2012 Springer Science+Business Media, LLC

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Waerzeggers, Y. et al. (2012). Positron Emission Tomography-Based Molecular Imaging. In: Martínez Murillo, R., Martínez, A. (eds) Animal Models of Brain Tumors. Neuromethods, vol 77. Humana Press, Totowa, NJ. https://doi.org/10.1007/7657_2012_36

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  • DOI: https://doi.org/10.1007/7657_2012_36

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-208-7

  • Online ISBN: 978-1-62703-209-4

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