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Tracking and Imaging of Transplanted Stem Cells in Animals

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Imaging and Tracking Stem Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2150))

Abstract

The shortage of organ donors has contributed to the rapid development of cell-based therapy in which stem cells are transplanted and administered to repair or regenerate damaged tissues or organs. The common sources of stem cells are embryonic, mesenchymal, stromal, and induced pluripotent cells. Despite the popularity of stem cell therapy, evaluation of the therapeutic efficiency of transplanted stem cells and their tracking in vivo remains a major challenge. Current imaging modalities such as magnetic resonance imaging, radionuclide imaging, and positron emission tomography have certain limitations such as toxicity, shorter circulation time, and higher cost. Here, we describe near-infrared imaging methods to track and monitor stem cell recruitment to the site of injury.

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Authors and Affiliations

  1. Department of Bioengineering, The University of Texas at Arlington, Arlington, TX, USA

    Tanmayee Rajeev Chikate & Liping Tang

Authors
  1. Tanmayee Rajeev Chikate
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  2. Liping Tang
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Corresponding author

Correspondence to Liping Tang .

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Editors and Affiliations

  1. Ottawa, ON, Canada

    Kursad Turksen

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Chikate, T.R., Tang, L. (2019). Tracking and Imaging of Transplanted Stem Cells in Animals. In: Turksen, K. (eds) Imaging and Tracking Stem Cells. Methods in Molecular Biology, vol 2150. Humana, New York, NY. https://doi.org/10.1007/7651_2019_275

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  • DOI: https://doi.org/10.1007/7651_2019_275

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0626-1

  • Online ISBN: 978-1-0716-0627-8

  • eBook Packages: Springer Protocols

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