Community-Associated Methicillin-Resistant Staphylococcus aureus Case Studies

  • Madeleine G. Sowash
  • Anne-Catrin Uhlemann
Part of the Methods in Molecular Biology book series (MIMB, volume 1085)

Abstract

Over the past decade, the emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has changed the landscape of S. aureus infections around the globe. Initially recognized for its ability to cause disease in young and healthy individuals without healthcare exposures as well as for its distinct genotype and phenotype, this original description no longer fully encompasses the diversity of CA-MRSA as it continues to expand its niche. Using four case studies, we highlight a wide range of the clinical presentations and challenges of CA-MRSA. Based on these cases we further explore the globally polygenetic background of CA-MRSA with a special emphasis on generally less characterized populations.

Key words

Methicillin-resistant Staphylococcus aureus (MRSA) Methicillin-susceptible S. aureus (MSSA) Community-associated (CA)-MRSA Hospital associated (HA)-MRSA 

Notes

Acknowledgment

This work was funded in part by grant K08 AI090013 from the National Institute of Health and the Paul A. Marks scholarship.

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Copyright information

© Springer Science+Business Media, LLC 2014

Authors and Affiliations

  • Madeleine G. Sowash
    • 1
  • Anne-Catrin Uhlemann
    • 1
  1. 1.Division of Infectious Diseases, Department of Medicine, College of Physicians & SurgeonsColumbia UniversityNew YorkUSA

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