Abstract
The olfactory mucosa, located in the nasal cavity, is the only nervous tissue that is exposed to the external environment and easily accessible in every living individual. In addition, this organ is home of a continuing neurogenesis that is sustained by a large population of stem cells. Here, we describe a method for biopsying olfactory mucosa from human nasal cavities and isolating multipotent adult stem cells that can be used to either identify biomarkers in brain disorders or repair the pathological/traumatized nervous system.
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Acknowledgments
This work was financially supported by ANR (Agence nationale de la Recherche), AFM (Association Française contre les Myopathies), FEDER in PACA and IRME (Institut de Recherche sur la Moelle épinière et l’Encéphale), the Australian Department of Health and Ageing, and the National Health and Medical Research Council of Australia.
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Féron, F., Perry, C., Girard, S.D., Mackay-Sim, A. (2013). Isolation of Adult Stem Cells from the Human Olfactory Mucosa. In: Reynolds, B., Deleyrolle, L. (eds) Neural Progenitor Cells. Methods in Molecular Biology, vol 1059. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-574-3_10
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DOI: https://doi.org/10.1007/978-1-62703-574-3_10
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-573-6
Online ISBN: 978-1-62703-574-3
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