Wound Regeneration and Repair pp 81-98

Part of the Methods in Molecular Biology book series (MIMB, volume 1037)

Adult Stem Cells in Small Animal Wound Healing Models

  • Allison C. Nauta
  • Geoffrey C. Gurtner
  • Michael T. Longaker
Protocol

Abstract

This chapter broadly reviews the use of stem cells as a means to accelerate wound healing, focusing first on the properties of stem cells that make them attractive agents to influence repair, both alone and as vehicles for growth factor delivery. Major stem cell reservoirs are described, including adult, embryonic, and induced pluripotent cell sources, outlining the advantages and limitations of each source as wound healing agents, as well as the possible mechanisms responsible for wound healing acceleration. Finally, the chapter includes a materials and methods section that provides an in-depth description of adult tissue harvest techniques.

Key words

Adult stem cells Adipose derived stromal cells Bone marrow derived mesenchymal cells 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Allison C. Nauta
    • 1
    • 2
  • Geoffrey C. Gurtner
    • 1
  • Michael T. Longaker
    • 1
    • 2
  1. 1.Hagey Laboratory for Pediatric and Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Institute of Stem Cell Biology and Regenerative MedicineStanford University School of MedicineStanfordUSA
  2. 2.Department of SurgeryStanford UniversityStanfordUSA

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