Abstract
In vivo wound healing experiments remain the most predictive models for studying human wound healing, allowing an accurate representation of the complete wound healing environment including various cell types, environmental cues, and paracrine interactions. Small animals are economical, easy to maintain, and allow researchers to take advantage of the numerous transgenic strains that have been developed to investigate the specific mechanisms involved in wound healing and regeneration. Here we describe three reproducible murine wound healing models that recapitulate the human wound healing process.
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Chen, J.S., Longaker, M.T., Gurtner, G.C. (2013). Murine Models of Human Wound Healing. In: Gourdie, R., Myers, T. (eds) Wound Regeneration and Repair. Methods in Molecular Biology, vol 1037. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-505-7_15
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DOI: https://doi.org/10.1007/978-1-62703-505-7_15
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-504-0
Online ISBN: 978-1-62703-505-7
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