Controlled Annotations for Systems Biology

  • Nick Juty
  • Camille Laibe
  • Nicolas Le Novère
Part of the Methods in Molecular Biology book series (MIMB, volume 1021)


The aim of this chapter is to provide sufficient information to enable a reader, new to the subject of Systems Biology, to create and use effectively controlled annotations, using resolvable Uniform Resource Identifiers (URIs). The text details the underlying requirements that have led to the development of such an identification scheme and infrastructure, the principles that underpin its syntax and the benefits derived through its use. It also places into context the relationship with other standardization efforts, how it differs from other pre-existing identification schemes, recent improvements to the system, as well as those that are planned in the future. Throughout, the reader is provided with explicit examples of use and directed to supplementary information where necessary.


Model Component Health Check Data Provider System Biology Markup Language Uniform Resource Identifier 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Nick Juty
    • 1
  • Camille Laibe
    • 2
  • Nicolas Le Novère
    • 3
  1. 1.The EMBL-European Bioinformatics InstituteCambridgeUK
  2. 2.EMBL Outstation–European Bioinformatics InstituteCambridgeUK
  3. 3.Babraham InstituteCambridgeUK

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