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Haemostasis pp 131-138 | Cite as

Thrombin Clotting Time

  • Vera Ignjatovic
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 992)

Abstract

Thrombin clotting time (TCT) is a coagulation assay used to diagnose congenital and acquired fibrinogen deficiency (Adcock et al., Coagulation handbook, Esoterix Coagulation, Austin, TX, 2002), as well as to identify contamination by heparin, prior to performing additional coagulation assays.

This test is based on the principle that in citrated plasma, the addition of Thrombin allows for formation of a stable clot. The time required for the formation of a stable clot is recorded in seconds and represents the actual TCT result.

Key words

TCT TT Coagulation test 

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Copyright information

© Humana Press 2013

Authors and Affiliations

  • Vera Ignjatovic
    • 1
    • 2
  1. 1.Haematology Research LaboratoryMurdoch Childrens Research InstituteMelbourneAustralia
  2. 2.Department of PaediatricsThe University of MelbourneMelbourneAustralia

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