Bioinformatics Identification of Antigenic Peptide: Predicting the Specificity of Major MHC Class I and II Pathway Players

  • Ole Lund
  • Edita Karosiene
  • Claus Lundegaard
  • Mette Voldby Larsen
  • Morten Nielsen
Part of the Methods in Molecular Biology™ book series (MIMB, volume 960)


Bioinformatics methods for immunology have become increasingly used over the last decade and now form an integrated part of most epitope discovery projects. This wide usage has led to the confusion of defining which of the many methods to use for what problems. In this chapter, an overview is given focusing on the suite of tools developed at the Technical University of Denmark.

Key words

Immune Epitope MHC, HLA Class I Class II Antigen processing Proteasome TAP Visualization Bioinformatics Prediction Web server. 


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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Ole Lund
    • 1
  • Edita Karosiene
    • 2
  • Claus Lundegaard
    • 1
  • Mette Voldby Larsen
    • 2
  • Morten Nielsen
    • 2
  1. 1.Department of Systems Biology, Center for Biological Sequence AnalysisTechnical University of DenmarkKongens LyngbyDenmark
  2. 2.Center for Biological Sequence Analysis, Department of Systems BiologyTechnical University of DenmarkKongens LyngbyDenmark

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