How to Use the IUPHAR Receptor Database to Navigate Pharmacological Data

  • Chidochangu P. Mpamhanga
  • Joanna L. Sharman
  • Anthony J. Harmar
  • NC-IUPHAR
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 897)

Abstract

Today’s data-intensive, interdisciplinary research challenges scientists to keep up to date with key experimental techniques and tools reported in the literature. The International Union of Basic and Clinical Pharmacology Database (IUPHAR-DB) goes some way to addressing this need by providing expert-curated information sourced from primary literature and displayed in a user-friendly manner online. The database provides a channel for the IUPHAR Nomenclature Committee (NC-IUPHAR) to provide recommendations on the nomenclature of receptors and ion channels, to document their properties and the ligands that are useful for receptor characterization. Here we describe IUPHAR-DB’s main features and provide examples of techniques for navigating and exploring the information. The database is freely available online at http://www.iuphar-db.org/.

Key words

Drug target Receptor GPCR Nuclear receptor Ion channel Pharmacology Ligand Experimental tool Biocuration Database 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Chidochangu P. Mpamhanga
    • 1
  • Joanna L. Sharman
    • 1
  • Anthony J. Harmar
    • 1
  • NC-IUPHAR
  1. 1.University/BHF Centre for Cardiovascular Science, University of EdinburghEdinburghUK

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