How to Use the IUPHAR Receptor Database to Navigate Pharmacological Data

  • Chidochangu P. Mpamhanga
  • Joanna L. Sharman
  • Anthony J. Harmar
Part of the Methods in Molecular Biology book series (MIMB, volume 897)


Today’s data-intensive, interdisciplinary research challenges scientists to keep up to date with key experimental techniques and tools reported in the literature. The International Union of Basic and Clinical Pharmacology Database (IUPHAR-DB) goes some way to addressing this need by providing expert-curated information sourced from primary literature and displayed in a user-friendly manner online. The database provides a channel for the IUPHAR Nomenclature Committee (NC-IUPHAR) to provide recommendations on the nomenclature of receptors and ion channels, to document their properties and the ligands that are useful for receptor characterization. Here we describe IUPHAR-DB’s main features and provide examples of techniques for navigating and exploring the information. The database is freely available online at

Key words

Drug target Receptor GPCR Nuclear receptor Ion channel Pharmacology Ligand Experimental tool Biocuration Database 


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Chidochangu P. Mpamhanga
    • 1
  • Joanna L. Sharman
    • 1
  • Anthony J. Harmar
    • 1
  1. 1.University/BHF Centre for Cardiovascular Science, University of EdinburghEdinburghUK

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