Modeling Experimental Design for Proteomics

Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 673)

Abstract

The complexity of proteomes makes good experimental design essential for their successful investigation. Here, we describe how proteomics experiments can be modeled and how computer simulations of these models can be used to improve experimental designs.

Key words

Proteomics Mass spectrometry Experimental design Simulations Modeling 

Notes

Acknowledgments

This work was supported by funding provided by the National Institutes of Health Grants RR00862 and RR022220, the Carl Trygger foundation, and the Swedish research council.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of ChemistrySwedish University of Agricultural SciencesUppsalaSweden
  2. 2.The Rockefeller UniversityNew YorkUSA

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