Hepatocytes pp 525-534

Part of the Methods in Molecular Biology book series (MIMB, volume 640)

Human Hepatocyte Transplantation

  • Anil Dhawan
  • Stephen C. Strom
  • Etienne Sokal
  • Ira J. Fox


Over the last decade the interest in hepatocyte transplantation has been growing continuously and this treatment may represent an alternative clinical approach for patients with acute liver failure and life-threatening liver-based metabolic disorders. The technology also serves as the proof of concept and reference for future development in stem cell technology. This chapter reviews the field of hepatocyte transplantation from bench to bedside.

Key words

Hepatocyte transplantation collagenase cryopreservation liver tissue source GMP laboratory metabolic liver disease acute liver failure stem cells immunosuppression 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Anil Dhawan
    • 1
  • Stephen C. Strom
    • 2
  • Etienne Sokal
    • 3
  • Ira J. Fox
    • 4
  1. 1.King’s Cell Isolation UnitKing’s College HospitalLondonUK
  2. 2.Department of PathologyUniversity of PittsburghPittsburghUSA
  3. 3.Pediatric DepartmentUniversité Catholique de LouvainBrusselsBelgium
  4. 4.Department of SurgeryUniversity of Nebraska Medical CenterOmahaUSA

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