Liposomes pp 295-303 | Cite as

Liposomes for Drug Delivery to Mitochondria

  • Sarathi V. Boddapati
  • Gerard G. M. D’Souza
  • Volkmar Weissig
Protocol
First Online:
Part of the Methods in Molecular Biology book series (MIMB, volume 605)

Abstract

Efficacy of therapeutically active drugs known to act on intracellular targets can be enhanced by specific delivery to the site of action. Triphenylphosphonium cations can be used to create subcellular targeted liposomes that efficiently deliver drugs to mitochondria, thus enhancing their therapeutic action.

Key words

Mitochondriotropics Mitochondrial medicine Mitochondrial nanocariers Mitochondrial drug delivery 
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Copyright information

© Humana Press, a part of Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Sarathi V. Boddapati
    • 1
  • Gerard G. M. D’Souza
    • 1
  • Volkmar Weissig
    • 2
  1. 1.Department of Pharmaceutical SciencesNortheastern UniversityBostonUSA
  2. 2.Department of Pharmaceutical SciencesMidwestern University College of Pharmacy GlendaleGlendaleUSA

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