Tissue Proteomics pp 193-220
Biorepository Standards and Protocols for Collecting, Processing, and Storing Human Tissues
Cell and Tissue Banking
Int’l. Ethical Guidelines for Biomediocal Res Involving Human Subjects
Book and On-line
Council for Int’l Orgs of Medical Sciences, World Health Org, Geneva, Switzerlandhttp://www.cioms.ch/
Collaborating with Commerical Tissue Biorepositories
The most commonly available tissues are formalin-fixed paraffin-embedded tissues (FFPET). While FFPET can be used for immunohistochemistry, certain DNA-based assays, and even RNA, frozen tissues are best suited for isolation and characterization of proteins and RNA. Freezers, back-up systems, monitors, and alarm systems and appropriate physical security are needed for long-term storage of frozen tissues. Other storage formats such as blotting onto filter paper for storage at room temperature are more commonly used for blood and can provide important “fingerprinting” for chain of custody, linking a given subject to a tissue sample.
Key WordsBiorepository tissue banking tissue preservation
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