Searching the Protein Interaction Space Through the MINT Database

  • Andrew Chatr-aryamontri
  • Andreas Zanzoni
  • Arnaud Ceol
  • Gianni Cesareni
Part of the Methods in Molecular Biology book series (MIMB, volume 484)


Many fundamental processes involve protein-protein interactions. Recent advances in technology make it possible to perform large-scale, genome-wide interaction mapping experiments that result in an always increasing amount of data. Protein-protein interaction databases are thus becoming a major resource for investigating biological networks and pathways. In this chapter we describe the Molecular INTeraction database (MINT). The MINT database aims at storing, in a structured format, information about protein-protein interactions (PPIs) by extracting experimental details from work published in peer-reviewed journals.

Key Words

Protein-protein interaction database protein networks 


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Copyright information

© Humana Press, Totowa, NJ 2008

Authors and Affiliations

  • Andrew Chatr-aryamontri
    • 1
  • Andreas Zanzoni
    • 1
  • Arnaud Ceol
    • 1
  • Gianni Cesareni
    • 1
  1. 1.Department of BiologyUniversity of Rome “Tor Vergata,”RomeItaly

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