Hepatitis C pp 329-336 | Cite as

Measuring HCV Infectivity Produced in Cell Culture and In Vivo

  • Brett D. Lindenbach
Part of the Methods in Molecular Biology™ book series (MIMB, volume 510)


Recently described systems for efficiently growing HCV in cell culture provide powerful new tools with which to dissect the life cycle of this important human pathogen. This chapter describes methods for measuring the infectivity of HCV produced in cell culture or recovered from animals experimentally infected with the cell culture–produced virus.

Key Words

Hepatitis C virus HCV titer infectivity assay 


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Copyright information

© Humana Press, a part of Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Brett D. Lindenbach
    • 1
  1. 1.Section of Microbial PathogenesisYale University School of MedicineNew HavenUSA

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