Application of Imaging and Other Noninvasive Techniques in Determining Adipose Tissue Mass

  • Wei Shen
  • Jun Chen
Part of the Methods in Molecular Biology™ book series (MIMB, volume 456)


In vivo adipose tissue quantification is an important tool to characterize phenotypes of obesity, especially in the human. The amount and distribution of adipose tissue is associated with many of the adverse consequences of obesity. Recent studies suggest that adipose tissue is not a single homogeneous compartment. Regional adipose tissue depots vary in biological functions and individual adipose tissue compartments have stronger associations with metabolic conditions than does total adipose tissue mass. Currently there is intense and increasing interest in regional adipose tissue compartments. Computed tomography and magnetic resonance imaging often are used to quantify adipose tissue volumes or cross-sectional adipose tissue areas. Other modalities, including dual-energy absorpti-ometry and magnetic resonance spectroscopy, provide whole-body or regional fat measures instead of adipose tissue mass quantification.

Key words

Magnetic resonance imaging computed tomography adipose tissue visceral adipose tissue subcutaneous adipose tissue intermuscular adipose tissue body composition abdominal obesity 


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Copyright information

© Humana Press, a part of Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Wei Shen
    • 1
  • Jun Chen
    • 2
  1. 1.Obesity Research Center, St. Luke's-Roosevelt Hospital and Institute of Human NutritionColumbia University College of Physicians and SurgeonsNew YorkUSA
  2. 2.Image Reading Lab, Obesity Research Center, St. Luke's-Roosevelt Hospital and Institute of Human NutritionColumbia University College of Physicians and SurgeonsNew YorkUSA

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