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Stem Cells in Regenerative Medicine

Volume 482 of the series Methods in Molecular Biology pp 55-90

Stem Cell Sources for Regenerative Medicine

  • Ali M. RiaziAffiliated withDepartment of Chemical Engineering and Applied Chemistry, University of Toronto
  • , Sarah Y. KwonAffiliated withInstitute of Biomaterials and Biomedical Engineering, University of Toronto
  • , William L. StanfordAffiliated withInstitute of Biomaterials and Biomedical Engineering, University of Toronto

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Abstract

Tissue-resident stem cells or primitive progenitors play an integral role in homeostasis of most organ systems. Recent developments in methodologies to isolate and culture embryonic and somatic stem cells have many new applications poised for clinical and preclinical trials, which will enable the potential of regenerative medicine to be realized. Here, we overview the current progress in therapeutic applications of various stem cells and discuss technical and social hurdles that must be overcome for their potential to be realized.

Key words

Stem cells cell therapy regeneration