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Using Toxins in Brain Slice Recordings

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Part of the Methods in Molecular Biology book series (MIMB,volume 2068)


Use of biological toxins from different kinds is widely accepted in electrophysiological experiments. In particular, electrophysiological recordings from brain tissue slices are usually conducted with toxins to manipulate on different receptors or ion channels. Here we describe usage of toxins in electrophysiological experiments in acute brain slices.

Key words

  • Brain slices
  • Electrophysiology
  • Field potential
  • Ion channels
  • Patch-clamp
  • Picrotoxin
  • Tetrodotoxin
  • Toxins

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  1. 1.

    Glass electrode preparation is not discussed in this chapter.


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Correspondence to Rami Yaka .

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Bingor, A., Yaka, R. (2020). Using Toxins in Brain Slice Recordings. In: Priel, A. (eds) Snake and Spider Toxins. Methods in Molecular Biology, vol 2068. Humana, New York, NY.

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-9844-9

  • Online ISBN: 978-1-4939-9845-6

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