Response Standardization for Drift Correction and Multivariate Calibration Transfer in “Electronic Tongue” Studies

  • Vitaly Panchuk
  • Valentin Semenov
  • Larisa Lvova
  • Andrey Legin
  • Dmitry Kirsanov
Part of the Methods in Molecular Biology book series (MIMB, volume 2027)


The procedures for response standardization in “electronic tongue” (ET) studies are described. The construction of reliable multivariate calibration for “electronic tongue” requires the analysis of a large number of representative samples both with ET and reference techniques. This is a laborious and expensive process. Long-term sensor array operation leads to the changes in sensor response characteristics and thus invalidates the multivariate predictive models. Moreover, due to the individual parameters of each sensor in different sensor arrays, it is not possible to use the calibration model for one system together with the data acquired by another system, even if they have the same sensors. Both of these issues lead to the necessity of frequent sensor array calibration which would be ideal to avoid. Instead of recalibration, these two problems can be handled using mathematical methods intended for sensor response standardization. This chapter describes two popular methods of standardization which can be used for both drift correction and calibration transfer. Thus, significant efforts on measuring representative sample sets for sensor array recalibration can be avoided.

Key words

Electronic tongue Multivariate calibration Response standardization Calibration transfer Drift correction 



This work was partially financially supported by Government of Russian Federation, Grant 08-08.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Vitaly Panchuk
    • 1
    • 2
  • Valentin Semenov
    • 1
  • Larisa Lvova
    • 2
    • 3
  • Andrey Legin
    • 1
    • 2
  • Dmitry Kirsanov
    • 1
    • 2
  1. 1.Institute of ChemistrySt. Petersburg State UniversitySt. PetersburgRussia
  2. 2.Laboratory of Artificial Sensory SystemsITMO UniversitySt. PetersburgRussia
  3. 3.Department of Chemical Science and TechnologiesUniversity “Tor Vergata”RomeItaly

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