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Animal Models of Eating Disorders

  • Maria Scherma
  • Roberto Collu
  • Valentina Satta
  • Elisa Giunti
  • Paola FaddaEmail author
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 2011)

Abstract

Eating disorders (EDs) include a range of chronic and disabling pathologies characterized by persistent maladaptive eating habits and/or behaviors aimed at controlling body shape and size, with important consequences on physical health. Different animal models of EDs have been developed to investigate pharmacological, environmental, and genetic determinants that contribute to the development and maintenance of these disorders as well as for the identification of potential therapeutic targets. In this chapter, we will provide an overview of the most useful animal models of EDs, focusing mainly on those used to study anorexia nervosa and binge eating disorder.

Key words

Eating disorders Anorexia nervosa Binge eating disorder Animal models Stress Palatable food Physical activity 

Notes

Acknowledgments

This work was funded by Ministero dell’Istruzione, dell’Università e della Ricerca (PRIN 2010), by Fondazione Banco di Sardegna (Prot. N.U. 627.213/A1.551. 2013), and by the Department of Biomedical Sciences Project (RICDIP_2012_Fratta_01) at the University of Cagliari. The authors are grateful to Marta Tuveri and Elena Vinci for technical assistance.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Maria Scherma
    • 1
  • Roberto Collu
    • 1
  • Valentina Satta
    • 1
  • Elisa Giunti
    • 1
  • Paola Fadda
    • 1
    • 2
    • 3
    • 4
    Email author
  1. 1.Department of Biomedical Sciences, Division of Neuroscience and Clinical PharmacologyUniversity of CagliariCagliariItaly
  2. 2.Centre of Excellence “Neurobiology of Addiction”University of CagliariCagliariItaly
  3. 3.CNR Institute of Neuroscience—Cagliari, National Research CouncilCagliariItaly
  4. 4.National Neuroscience InstituteCagliariItaly

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