Animal Models of Eating Disorders
Eating disorders (EDs) include a range of chronic and disabling pathologies characterized by persistent maladaptive eating habits and/or behaviors aimed at controlling body shape and size, with important consequences on physical health. Different animal models of EDs have been developed to investigate pharmacological, environmental, and genetic determinants that contribute to the development and maintenance of these disorders as well as for the identification of potential therapeutic targets. In this chapter, we will provide an overview of the most useful animal models of EDs, focusing mainly on those used to study anorexia nervosa and binge eating disorder.
Key wordsEating disorders Anorexia nervosa Binge eating disorder Animal models Stress Palatable food Physical activity
This work was funded by Ministero dell’Istruzione, dell’Università e della Ricerca (PRIN 2010), by Fondazione Banco di Sardegna (Prot. N.U. 627.213/A1.551. 2013), and by the Department of Biomedical Sciences Project (RICDIP_2012_Fratta_01) at the University of Cagliari. The authors are grateful to Marta Tuveri and Elena Vinci for technical assistance.
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