Construction and Analysis of miRNA Regulatory Networks

  • Antonella Mensi
  • Vincenzo Bonnici
  • Simone Caligola
  • Rosalba GiugnoEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1970)


This chapter is devoted to illustrate the usage of state-of-the-art methodologies for miRNA regulatory network construction and analysis. Advantages in understanding the role of miRNAs in regulating gene expression are increasing the possibility of developing targeted therapies and drugs. This new possibility can be exploited by gaining new knowledge through analyzing interactions between a specific miRNA and a targeted gene.

Key words

miRNA networks miRNA targets Enrichment analysis Expression data Network analysis 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Antonella Mensi
    • 1
  • Vincenzo Bonnici
    • 1
  • Simone Caligola
    • 1
  • Rosalba Giugno
    • 1
    Email author
  1. 1.Department of Computer ScienceUniversity of VeronaVeronaItaly

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