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Metabolomics: A Microbial Physiology and Metabolism Perspective

  • Chijioke J. Joshua
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1859)

Abstract

Metabolomics is valuable for studying microbial metabolism, which is often used to elucidate biological functions. Effective application of metabolomics is enhanced by fundamental understanding of microbial physiology and metabolism. This review briefly highlights important aspects of metabolism that are essential for designing and executing effective metabolic and metabolomics studies. The influence of microbial physiology and metabolism on growth, energy metabolism and regulation is briefly reviewed. The chapter also evaluates factors affecting metabolic prediction.

Key words

Microbial physiology Microbial metabolism Microbial growth Central carbon metabolism Metabolic regulation Experimental design Metabolic pathways 

Notes

Acknowledgments

This work was part of the DOE Joint BioEnergy Institute (http://www.jbei.org) supported by the US Department of Energy, Office of Science, Office of Biological and Environmental Research, through contract DE-AC02-05CH11231 between Lawrence Berkeley National Laboratory and the US Department of Energy.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Chijioke J. Joshua
    • 1
    • 2
  1. 1.Biological Systems and Engineering DivisionLawrence Berkeley National LaboratoryBerkeleyUSA
  2. 2.Joint BioEnergy InstituteEmeryvilleUSA

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