Adaptive Laboratory Evolution for Enhanced Carotenoid Production in Microalgae
In order to produce natural pigments with competitive prices, algal strains employed in industrial production need to be improved for increasing the productivity of valuable metabolites, thereby reducing the overall production cost. Adaptive laboratory evolution (ALE) is a traditional method for strain improvement, which has been effectively utilized in bacteria and fungi. With the growing interest in algal biotechnology, attempts have recently been put forward to improve microalgal strains with ALE approach. This chapter describes a stepwise adaptive evolution strategy that enhances carotenoid yield from microalgae.
Key wordsCarotenoids Adaptive laboratory evolution (ALE) Abiotic stress Green algae Response surface methodology (RSM) Dunaliella salina
This work was supported by Icelandic Technology Development Fund with a grant number of 163922-0611.
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