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Reactions in NMR Tubes as Key Weapon in Rational Drug Design

  • Dimitrios Ntountaniotis
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1824)

Abstract

NMR spectroscopy is a powerful technique suitable for obtaining detailed structural and dynamic data at atomic resolution. Progress in NMR instrumentation has led the scientific community to produce novel techniques which provide valuable information to resolve demanding and crucial questions of molecular biology and rational drug design. This chapter outlines the progress of NMR spectroscopy in the rational drug design. In addition, it offers an example of a reaction in NMR tube for achieving rational drug design.

Key words

NMR spectroscopy for liquids Structural properties Drug design and discovery 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Dimitrios Ntountaniotis
    • 1
  1. 1.Department of Chemistry, Laboratory of Organic ChemistryNational and Kapodistrian University of AthensAthensGreece

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