Analysis of Drugs of Abuse by Gas Chromatography–Mass Spectrometry (GC-MS)
Analysis of drugs of abuse constitutes a major portion of work for many crime laboratories. The most important and most utilized technique for the screening and identification of solid-dosage drugs is gas chromatography–mass spectrometry (GC-MS). A detailed practical procedure is described for the rapid screening and identification by GC-MS of most drugs of abuse that are commonly encountered in forensic drug laboratories.
Key wordsDrug analysis Controlled substances Drugs of abuse Seized drugs GC-MS
- 2.Bellman SW (1968) Mass spectral identification of some hallucinogenic drugs. J AOAC Int 51:164–178Google Scholar
- 4.Scientific Working Group for the Analysis of Seized Drugs (SWGDRUG) http://www.swgdrug.org/approved.htm. Last accessed 22 May 2017
- 5.ASTM E-2329 Practice for the identification of seized drugs. ASTM International, West Conshohocken, PA E-2729-17 (2017)Google Scholar
- 7.Adair AR, Noggle FT, Odom MS, Rhodes MA (1983) The ANOR (alternate non-aqueous organic ratio) extraction procedure. Micrograms XVI 1:220–228Google Scholar
- 8.Saloom JM (1983) Use of the ANOR method for separation of propoxyphene from propoxyphene + APC. Micrograms XVI 1:229–231Google Scholar