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Searching and Extracting Data from the EMBL-EBI Complex Portal

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Protein Complex Assembly

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1764))

Abstract

The Complex Portal (www.ebi.ac.uk/complexportal) is an encyclopedia of macromolecular complexes. Complexes are assigned unique, stable IDs, are species specific, and list all participating members with links to an appropriate reference database (UniProtKB, ChEBI, RNAcentral). Each complex is annotated extensively with its functions, properties, structure, stoichiometry, tissue expression profile, and subcellular location. Links to domain-specific databases allow the user to access additional information and enable data searching and filtering. Complexes can be saved and downloaded in PSI-MI XML, MI-JSON, and tab-delimited formats.

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Acknowledgment

This work was supported by European Molecular Biology Laboratories core funding, BBSRC Midas Grant (BB/L024179/1), and the Wellcome Trust (WT101477MA) (Complex Viewer, as part of PRIDE Atlas). We thank Mila Rodrigues and Luana Perfetto for their curation efforts, Maximilian Koch for developing the website, Xavier Watkins and Sangya Pundir for their user experience design expertise, and Colin Combe for writing ComplexViewer for this project.

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Authors and Affiliations

  1. European Molecular Biology Laboratories, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, Cambridgeshire, UK

    Birgit H. M. Meldal & Sandra Orchard

Authors
  1. Birgit H. M. Meldal
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  2. Sandra Orchard
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Corresponding author

Correspondence to Birgit H. M. Meldal .

Editor information

Editors and Affiliations

  1. MRC Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom

    Joseph A. Marsh

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Meldal, B.H.M., Orchard, S. (2018). Searching and Extracting Data from the EMBL-EBI Complex Portal. In: Marsh, J. (eds) Protein Complex Assembly. Methods in Molecular Biology, vol 1764. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7759-8_24

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  • DOI: https://doi.org/10.1007/978-1-4939-7759-8_24

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7758-1

  • Online ISBN: 978-1-4939-7759-8

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