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Hyperlocomotion Test for Assessing Behavioral Disorders

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Book cover Investigations of Early Nutrition Effects on Long-Term Health

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1735))

Abstract

Under- or overfeeding during pregnancy can lead to behavioral deficits in the offspring in later life. Here, we present a protocol for setting up and carrying out the hyperlocomotion test for assessing behavioral symptoms such as psychosis or mania. As an example, we use the acute rat phencyclidine-injection model which exhibits hyperlocomotion and stereotypic behaviors, resembling the positive symptoms of schizophrenia.

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Author information

Authors and Affiliations

  1. Department of Neurosciences, University of Cambridge, Cambridge, UK

    Dan Ma

  2. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil

    Paul C. Guest

Authors
  1. Dan Ma
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  2. Paul C. Guest
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Corresponding author

Correspondence to Paul C. Guest .

Editor information

Editors and Affiliations

  1. Debden, Essex, United Kingdom

    Paul C. Guest

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Ma, D., Guest, P.C. (2018). Hyperlocomotion Test for Assessing Behavioral Disorders. In: Guest, P. (eds) Investigations of Early Nutrition Effects on Long-Term Health. Methods in Molecular Biology, vol 1735. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7614-0_29

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  • DOI: https://doi.org/10.1007/978-1-4939-7614-0_29

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7613-3

  • Online ISBN: 978-1-4939-7614-0

  • eBook Packages: Springer Protocols

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