UniProt Protein Knowledgebase

  • Sangya PundirEmail author
  • Maria J. Martin
  • Claire O’Donovan
Part of the Methods in Molecular Biology book series (MIMB, volume 1558)


The Universal Protein Resource (UniProt) is a freely available comprehensive resource for protein sequence and annotation data. UniProt is a collaboration between the European Bioinformatics Institute (EMBL-EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR). Across the three institutes more than 100 people are involved through different tasks such as expert curation, software development, and support.

This chapter introduces the functionality and data provided by UniProt. It describes example use cases for which you might come to UniProt and the methods to help you achieve your goals.

Key words

UniProt Protein data Protein tools 



This work was supported by grant U41HG007822 from the National Institutes of Health.


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Copyright information

© Springer Science+Business Media LLC 2017

Authors and Affiliations

  • Sangya Pundir
    • 1
    Email author
  • Maria J. Martin
    • 1
  • Claire O’Donovan
    • 1
  1. 1.European Molecular Biology LaboratoryEuropean Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, HinxtonCambridgeUK

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