Drosophila pp 291-302 | Cite as

Protocols to Study Aging in Drosophila

Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1478)

Abstract

The fruit fly Drosophila melanogaster offers a host of advantages for studying the biology of aging: a well-understood biology, a wide range of genetic reagents, well-defined dietary requirements, and a relatively short life span, with a median of ~80 days and maximum ~100 days. Several phenotypes can be used to assess the aging process, but the simplest and most widely used metric is length of life. Here we describe a standard life span assay for Drosophila housed on a simple sugar/yeast diet.

Key words

Drosophila melanogaster Life span Aging Method Diet Genetic interventions Pharmacological interventions Backcross 

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Institute of Healthy Ageing and Department Genetics, Evolution and EnvironmentUniversity College LondonLondonUK
  2. 2.Max Planck Institute for Biology of AgeingKölnGermany
  3. 3.School of Biological SciencesMonash UniversityClaytonAustralia

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