A Practical Guide to The Cancer Genome Atlas (TCGA)

  • Zhining WangEmail author
  • Mark A. Jensen
  • Jean Claude Zenklusen
Part of the Methods in Molecular Biology book series (MIMB, volume 1418)


The Cancer Genome Atlas (TCGA) is one of the most ambitious and successful cancer genomics programs to date. The TCGA program has generated, analyzed, and made available genomic sequence, expression, methylation, and copy number variation data on over 11,000 individuals who represent over 30 different types of cancer. This chapter provides a brief overview of the TCGA program and detailed instructions and tips for investigators on how to find, access, and download this data.

Key words

TCGA The Cancer Genome Atlas Cancer genomics Next-generation sequencing Mutation Methylation Proteomics Transcriptome Copy number miRNA 


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Zhining Wang
    • 1
    Email author
  • Mark A. Jensen
    • 2
  • Jean Claude Zenklusen
    • 1
  1. 1.Center for Cancer GenomicsNational Cancer Institute, National Institutes of HealthBethesdaUSA
  2. 2.Research Administration DirectorateLeidos Biomedical Research Inc., Frederick National Laboratory for Cancer ResearchFrederickUSA

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