The Accessory Limb Model: An Alternative Experimental System of Limb Regeneration
Accessory limb model (ALM) was developed as an experimental model and functional assay for limb regeneration. The ALM provides several ways to identify pathways and test for signaling molecules that regulate limb regeneration. Here, we summarize the history of the ALM and describe the specific details involved in inducing ectopic blastemas and limbs from a skin wound on the side of the arm.
Key wordsSalamander Axolotl Nerve Limb regeneration Slow-release sustained bead
This work was supported by Grant-in-Aid for Scientific Research on Innovative Areas (KAKENHI #23124508 to AS and #22124006 to TE).
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