Mitochondrial Medicine pp 219-229 | Cite as
In Vivo Assessment of Mitochondrial Oxygen Consumption
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Abstract
The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) has been proposed by us as a potential clinical noninvasive tool for monitoring mitochondrial function. We have been working on the development of mitochondrial respirometry for monitoring mitochondrial oxygen tension (mitoPO2) and mitochondrial oxygen consumption (mitoVO2) in skin. In this work we describe the principles of the method in experimental animals.
Key words
Oxygen-dependent quenching Mitochondrial oxygen tension (mitoPO2) Mitochondrial oxygen consumption (mitoVO2) Phosphorescence quenching Tissue oxygenationReferences
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