The Synthetic Biology Open Language

  • Chris Myers
  • Kevin Clancy
  • Goksel Misirli
  • Ernst Oberortner
  • Matthew Pocock
  • Jacqueline Quinn
  • Nicholas Roehner
  • Herbert M. Sauro
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1244)

Abstract

The design and construction of engineered organisms is an emerging new discipline called synthetic biology and holds considerable promise as a new technological platform. The design of biologically engineered systems is however nontrivial, requiring contributions from a wide array of disciplines. One particular issue that confronts synthetic biologists is the ability to unambiguously describe novel designs such that they can be reengineered by a third-party. For this reason, the synthetic biology open language (SBOL) was developed as a community wide standard for formally representing biological designs. A design created by one engineering team can be transmitted electronically to another who can then use this design to reproduce the experimental results. The development and the community of the SBOL standard started in 2008 and has since grown in use with now over 80 participants, including international, academic, and industrial interests. SBOL has stimulated the development of repositories and software tools to help synthetic biologists in their design efforts. This chapter summarizes the latest developments and future of the SBOL standard and its supporting infrastructure.

Key words

Synthetic biology Standards Engineering design 

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Chris Myers
    • 1
  • Kevin Clancy
    • 2
  • Goksel Misirli
    • 3
  • Ernst Oberortner
    • 4
  • Matthew Pocock
    • 3
  • Jacqueline Quinn
    • 5
  • Nicholas Roehner
    • 1
  • Herbert M. Sauro
    • 6
  1. 1.Dept. of Electrical and Computer EngineeringUniversity of UtahSalt Lake CityUSA
  2. 2.Synthetic Biology UnitLife TechnologiesCarlsbadUSA
  3. 3.School of Computing ScienceNewcastle UniversityNewcastle upon TyneUK
  4. 4.Dept. of Electrical and Computer EngineeringBoston UniversityBostonUSA
  5. 5.Bio Nano Programmable MatterAutodesk ResearchSan FranciscoUSA
  6. 6.Department of BioengineeringUniversity of WashingtonSeattleUSA

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