Comparative Genomic Analysis at the PATRIC, A Bioinformatic Resource Center
The Pathosystems Resource Integration Center (PATRIC) is a genomics-centric relational database and bioinformatics resource designed to assist scientists in infectious-disease research. This method paper provides detailed instructions on using this resource to finding data specific to genomes, saving it in a personalized workspace and using a variety of interactive tools to analyze that data. While PATRIC contains many diverse tools and functionalities to explore both genome-scale and gene expression data, the main focus of this chapter is on comparative analysis of bacterial genomes.
Key wordsComparative genomics Metabolomics Metadata Phylogeny Genome analysis tools
- 1.Greene JM, Plunkett G 3rd, Burland V, Glasner J, Cabot E et al (2007) A new asset for pathogen informatics – the Enteropathogen Resource Integration Center (ERIC), an NIAID Bioinformatics Resource Center for Biodefense and Emerging/Re-emerging Infectious Disease. Adv Exp Med Biol 603:28–42PubMedCrossRefGoogle Scholar