Comparative Genomic Analysis at the PATRIC, A Bioinformatic Resource Center

  • Alice R. WattamEmail author
  • Joseph L. Gabbard
  • Maulik Shukla
  • Bruno W. Sobral
Part of the Methods in Molecular Biology book series (MIMB, volume 1197)


The Pathosystems Resource Integration Center (PATRIC) is a genomics-centric relational database and bioinformatics resource designed to assist scientists in infectious-disease research. This method paper provides detailed instructions on using this resource to finding data specific to genomes, saving it in a personalized workspace and using a variety of interactive tools to analyze that data. While PATRIC contains many diverse tools and functionalities to explore both genome-scale and gene expression data, the main focus of this chapter is on comparative analysis of bacterial genomes.

Key words

Comparative genomics Metabolomics Metadata Phylogeny Genome analysis tools 



This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272200900040C, awarded to BWS Sobral.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Alice R. Wattam
    • 1
    Email author
  • Joseph L. Gabbard
    • 1
  • Maulik Shukla
    • 1
  • Bruno W. Sobral
    • 1
  1. 1.Virginia Bioinformatics InstituteVirginia TechBlacksburgUSA

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