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Circadian Clocks pp 149–156Cite as

Circadian Metabolomics from Breath

Part of the Methods in Molecular Biology book series (MIMB,volume 2130)

Abstract

Metabolites like melatonin are essential in determining circadian phase. In the recent years, comprehensive metabolome analyses have unveiled entire panels of small biomolecules fluctuating in a circadian fashion, thus enabling a more precise determination of inner time and understanding of how circadian clock operates at the molecular level. Emerging analytical techniques allowing for the determination of exhaled metabolites in breath show promise to gain further insights noninvasively and in vivo into circadian metabolism.

Key words

  • Metabolomics
  • Breath analysis
  • Real-time analysis
  • Secondary electrospray ionization

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Author information

Authors and Affiliations

  1. Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland

    Steven A. Brown

  2. University Children’s Hospital Basel, University of Basel, Basel, Switzerland

    Pablo Sinues

  3. Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland

    Pablo Sinues

Authors
  1. Steven A. Brown
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  2. Pablo Sinues
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Corresponding author

Correspondence to Pablo Sinues .

Editor information

Editors and Affiliations

  1. Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zurich, Zürich, Switzerland

    Dr. Steven A. Brown

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Brown, S.A., Sinues, P. (2021). Circadian Metabolomics from Breath. In: Brown, S.A. (eds) Circadian Clocks. Methods in Molecular Biology, vol 2130. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0381-9_11

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  • DOI: https://doi.org/10.1007/978-1-0716-0381-9_11

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  • Publisher Name: Humana, New York, NY

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  • Online ISBN: 978-1-0716-0381-9

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