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Circadian Metabolomics from Breath

Part of the Methods in Molecular Biology book series (MIMB,volume 2130)

Abstract

Metabolites like melatonin are essential in determining circadian phase. In the recent years, comprehensive metabolome analyses have unveiled entire panels of small biomolecules fluctuating in a circadian fashion, thus enabling a more precise determination of inner time and understanding of how circadian clock operates at the molecular level. Emerging analytical techniques allowing for the determination of exhaled metabolites in breath show promise to gain further insights noninvasively and in vivo into circadian metabolism.

Key words

  • Metabolomics
  • Breath analysis
  • Real-time analysis
  • Secondary electrospray ionization

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  • DOI: 10.1007/978-1-0716-0381-9_11
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Correspondence to Pablo Sinues .

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Brown, S.A., Sinues, P. (2021). Circadian Metabolomics from Breath. In: Brown, S.A. (eds) Circadian Clocks. Methods in Molecular Biology, vol 2130. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0381-9_11

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  • DOI: https://doi.org/10.1007/978-1-0716-0381-9_11

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  • Publisher Name: Humana, New York, NY

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