Overview of Immobilized Enzymes’ Applications in Pharmaceutical, Chemical, and Food Industry

  • Alessandra BassoEmail author
  • Simona Serban
Part of the Methods in Molecular Biology book series (MIMB, volume 2100)


The use of immobilized enzymes in industry is becoming a routine process for the manufacture of many key compounds in the pharmaceutical, chemical, and food industry. Some enzymes like lipases are naturally robust and efficient, can be used for the production of many different molecules, and have found broad industrial applications. Some more specific enzymes, like transaminases, have required protein engineering to become suitable for applications in industrial manufacture. For all enzymes, the possibility to be immobilized and used in a heterogeneous form brings important industrial and environmental advantages such as simplified downstream processing or continuous process operations. Here, we present a series of large-scale applications of immobilized enzymes with benefits for the food, chemical, pharmaceutical, cosmetics, and medical device industries, some of them hardly reported before.

Key words

Biocatalysis Immobilized enzymes Industrial applications Food Pharmaceutical Chemical Cosmetic Medical devices Biosensors 


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© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Purolite, Unit D, Llantrisant Business ParkLlantrisantUK

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