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Wildlife Sentinels for Human and Environmental Health Hazards in Ecotoxicological Risk Assessment

  • Antonio Juan García-FernándezEmail author
  • Silvia Espín
  • Pilar Gómez-Ramírez
  • Emma Martínez-López
  • Isabel Navas
Protocol
Part of the Methods in Pharmacology and Toxicology book series (MIPT)

Abstract

Can animals reflect human and environmental health risks? This is a frequently asked question in the research community. Sentinel species are organisms that can provide early warning signs of potential risks to humans, so that preventive measures can be taken in time to avoid serious adverse health consequences. In spite of the well-known cases of use of sentinel species, animals are continuously offering information that in most cases is underestimated or incorrectly interpreted. Many species may be successfully used as sentinels or monitors of environmental and health hazards; however, there is no ideal species for all types of scenarios and conditions. For this reason, the advantages and disadvantages on the use of potential sentinel species and the main characteristics they should gather to be effective sentinels are discussed. Although a wide range of wildlife species are considered good candidates for biomonitoring purposes, bird species are especially suitable as biomonitors of environmental quality and to estimate human health risks.

During the last two decades, the effects induced by endocrine-disrupting chemicals (EDCs) on hormone action have been widely tested. Since the mid-twentieth century, it is well-known that humans and wildlife species are simultaneously exposed to multiple chemicals from multiple sources with potential ability to disrupt the endocrine system by different pathways and/or interfere with hormone actions. Moreover, additive effects related to this chemical cocktail exposure could be expected, increasing the potential risks to animal and human health. In addition, carcinogenic, immunotoxic, neurotoxic, behavioral, and other chronic effects are observed in wildlife, which are closely linked to human diseases.

Key words

Wildlife Sentinel animals Ecotoxicological risk Free-living animals Human health Environmental health Biomonitoring Endocrine disruption Cancer Immunotoxicity Neurotoxicity Behavioral effects 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  • Antonio Juan García-Fernández
    • 1
    Email author
  • Silvia Espín
    • 1
  • Pilar Gómez-Ramírez
    • 1
  • Emma Martínez-López
    • 1
  • Isabel Navas
    • 1
  1. 1.Toxicology and Risk Assessment Group, Department of Health SciencesBiomedical Research Institute of Murcia (IMIB-Arrixaca), Faculty of Veterinary, University of MurciaCampus de EspinardoSpain

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