Skin Wound Healing: Refractory Wounds and Novel Solutions

  • Gabriel M. Virador
  • Lola de Marcos
  • Victoria M. ViradorEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1879)


This overview of the current state of skin wound healing includes in vitro and in vivo approaches along with some recent clinical trials. From an introduction to wound healing, to tissue engineering as applied to the skin, we cover the basis for the current wound care techniques as well as novel and promising approaches. Special emphasis is given to refractory wounds which include wounds in diabetic patients. Natural compounds have been ever present in wound healing, and so we devote a section to highlighting current attempts to understand their mechanisms and to use them in novel ways.


Biomaterials Cellular therapies Natural compounds Refractory wounds Stem cells Tissue engineering Wound healing 



Our undergraduate research (course number SCIR297) is conducted with the support of Montgomery College. We thank our students Nhi Luu and Rachel Tannenbaum for contributing ideas to the project. We also thank Jung Wha Lee and Lauren Kimlin (Virador and Associates) for their support. We appreciate our lively discussions with Jacqueline Muller and her critical reading of the manuscript.


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Copyright information

© Springer Science+Business Media New York 2018

Authors and Affiliations

  • Gabriel M. Virador
    • 1
    • 2
  • Lola de Marcos
    • 2
  • Victoria M. Virador
    • 1
    • 3
    Email author
  1. 1.Biology DepartmentMontgomery CollegeRockvilleUSA
  2. 2.University of NavarraPamplonaSpain
  3. 3.Virador and AssociatesBethesdaUSA

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