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Homologous Recombination in Plants: An Antireview

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Plant Chromosome Engineering

Part of the book series: Methods in Molecular Biology ((MIMB,volume 701))

Abstract

Homologous recombination (HR) is a central cellular process involved in many aspects of genome maintenance such as DNA repair, replication, telomere maintenance, and meiotic chromosomal segregation. HR is highly conserved among eukaryotes, contributing to genome stability as well as to the generation of genetic diversity. It has been intensively studied, for almost a century, in plants and in other organisms. In this antireview, rather than reviewing existing knowledge, we wish to underline the many open questions in plant HR. We will discuss the following issues: how do we define homology and how the degree of homology affects HR? Are there any plant-specific HR qualities, how extensive is functional conservation and did HR proteins acquire new functions? How efficient is HR in plants and what are the cis and the trans factors that regulate it? Finally, we will give the prospects for enhancing the rates of gene targeting and meiotic HR for plant breeding purposes.

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Acknowledgments

We would like to thank Dr. Even-Faitelson and Dr. Samach for useful comments and the EU-FP7 Recbreeb and US-Israel BARD grants for financial support.

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Authors and Affiliations

  1. Department of Plant Sciences, The Weizmann Institute of Science, Rehovot, Israel

    Michal Lieberman-Lazarovich & Avraham A. Levy

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  1. Michal Lieberman-Lazarovich
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  2. Avraham A. Levy
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Correspondence to Avraham A. Levy .

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  1. , Division of Biological Sciences, University of Missouri, Tucker Hall 117, Columbia, 65211, Missouri, USA

    James A. Birchler

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Lieberman-Lazarovich, M., Levy, A.A. (2011). Homologous Recombination in Plants: An Antireview. In: Birchler, J. (eds) Plant Chromosome Engineering. Methods in Molecular Biology, vol 701. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61737-957-4_3

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  • DOI: https://doi.org/10.1007/978-1-61737-957-4_3

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