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  • Book
  • © 2012

Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy

Authors:

  • Nominated by Max-Planck-Institute for Polymer Research, Mainz, Germany
  • Innovative approach to assess the topic
  • Delivers remarkable new insights into materials
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Theses (Springer Theses)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-xvi
  2. General Introduction

    • Matthias J. N. Junk
    Pages 1-6
  3. Electron Paramagnetic Resonance Theory

    • Matthias J. N. Junk
    Pages 7-52
  4. The Functional Structure of Human Serum Albumin

    • Matthias J. N. Junk
    Pages 53-81
  5. Conclusion

    • Matthias J. N. Junk
    Pages 173-175
  6. Back Matter

    Pages 177-212

About this book

In his thesis, Matthias Junk takes an innovative approach to assess the local structure and dynamics of biological and synthetic amphiphilic macromolecules capable of transporting small molecules. Replacing the latter with stable radicals, he uses state-of-the-art electron paramagnetic resonance (EPR) spectroscopy to describe the highly relevant transport function from the viewpoint of the guest molecules. Such, he demonstrates that the functional structure of human serum albumin in solution significantly differs from its crystal structure – a consequence of the protein’s adaptability to host various endogenous compounds and drug molecules. Further, he shows that the thermal collapse of thermoresponsive hydrogels and dendronized polymers leads to static and dynamic heterogeneities on the nanoscale. These heterogeneities bear consequences for the material’s hosting properties and enable unforeseen complex catalytic functionalities.

Authors and Affiliations

  • , Dept. of Chemical Engineering, University of California, Santa Barbara, USA

    Matthias J.N.Junk

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access