Authors:
First advanced text for life scientists on numerical methods
Easy step-by-step introduction to numerical solutions
Installation guide for the free software GNU Octave
More than 30 programs (written in Octave) will provide templates for biochemical applications – available as supplementary electronic material
Analysis of experimental data by multi-parameter fits
Correlation of parameters, significance of the results
Includes supplementary material: sn.pub/extras
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Table of contents (9 chapters)
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Front Matter
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Back Matter
About this book
Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered.
Authors and Affiliations
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AG Biochemische Analytik, MPI für Molekulare Physiologie, Dortmund, Germany
Heino Prinz
Bibliographic Information
Book Title: Numerical Methods for the Life Scientist
Book Subtitle: Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB
Authors: Heino Prinz
DOI: https://doi.org/10.1007/978-3-642-20820-1
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2011
Hardcover ISBN: 978-3-642-20819-5Published: 06 August 2011
Softcover ISBN: 978-3-662-50587-8Published: 23 August 2016
eBook ISBN: 978-3-642-20820-1Published: 06 August 2011
Edition Number: 1
Number of Pages: IX, 149
Topics: Bioinformatics, Computational Biology/Bioinformatics, Mathematical and Computational Biology