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Biological Calcification

Normal and Pathological Processes in the Early Stages

  • Book
  • © 2007

Overview

Authors:
  1. Ermanno Bonucci

    1. Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza — Policlinico Umberto I, Roma, Italia

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  • Author has been involved in studies of biological calcification for over forty years

  • Plain, concise, and easy to read

  • Developing quite slowly; thus the book might become a reference source for many years to come

  • Set to become an important reference source for the shelves of bone densitometry labs across the world

  • Includes supplementary material: sn.pub/extras

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Table of contents (19 chapters)

  1. Front Matter

    Pages I-XXI
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  2. Introduction

    Pages 1-4

  3. Historical Notes

    Pages 5-21

  4. Methodology

    Pages 23-66

  5. The Nature and Composition of the Inorganic Phase

    Pages 67-103

  6. The Shape of Inorganic Particles

    Pages 105-144

  7. The Size of Inorganic Particles

    Pages 145-165

  8. Calcifying Matrices: Bone and Tendons

    Pages 167-230

  9. Calcifying Matrices: Dentin and Cementum

    Pages 231-259

  10. Calcifying Matrices: Cartilage

    Pages 261-301

  11. Calcifying Matrices: Enamel

    Pages 303-333

  12. Calcifying Matrices: Lower Vertebrates

    Pages 335-343

  13. Calcifying Matrices: Invertebrates

    Pages 345-366

  14. Calcifying Matrices: Non-skeletal Structures

    Pages 367-383

  15. Calcifying Matrices: Pathological Calcifications

    Pages 385-415

  16. Calcifying Matrices: Acquired or Experimental Diseases; Heritable Disorders; Genetically Modified Animals

    Pages 417-441

  17. The Organic-inorganic Relationships in Calcifying Matrices

    Pages 443-489

  18. Main Suggested Calcification Mechanisms: Cells

    Pages 491-506

  19. Main Suggested Calcification Mechanisms: Extracellular Matrix

    Pages 507-558

  20. Conclusions

    Pages 559-568
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Keywords

About this book

This book follows a precursor volume devoted to biological calci?cation, - sued by the CRC Press, Boca Raton (Florida) in 1992. Several basic aspects of the calci?cation process were analyzed in it by outstanding authors who had unquestioned competence in their respective research areas. Its main aim was that of giving readers access to a series of papers which, even though they discussed divergent aspects of biological calci?cations drawn from the study of systems as different as vertebrate skeletons and mollusks, in vitro cultures and unicellular organisms, ectopic calci?cation and urinary stones, provided elements permitting a coherent approach to a comprehensive view of the calci?cation process in biological tissues. Now, almost 15 years after the publication of that book, a great variety of new data from a wide spectrum of biological organisms and systems has enriched our knowledge of the normal and pathological mechanisms which can lead to calci?cation. Even so, this whole process is still problematic: the new knowledge, concepts and ideas have often suggested that a de?nitive solution was close at hand, but the local mechanism through which the inorganic substance is laid down in organic matrices continues to be an elusive, largely enigmatic topic.

Authors and Affiliations

  • Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza — Policlinico Umberto I, Roma, Italia

    Ermanno Bonucci

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