Overview
Presents up-to-date information in this exciting research area
Summarizes major advances made on hedgehog signaling mechanisms, activation of the pathway in various human cancer types
Highlights current challenges in our efforts to translate the basic biology into clinic
Provides insightful views suitable for graduate, undergraduate, and medical students, basic and clinical scientists, cancer patients as well as the general public
Includes supplementary material: sn.pub/extras
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Table of contents (12 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics. The hedgehog pathway is a major pathway regulating cell differentiation, tissue polarity, stem cell maintenance and cell proliferation. It is known by now that activation of this pathway occurs in a variety of human cancer, including basal cell carcinomas (BCCs), medulloblastomas, leukemia, gastrointestinal, lung, ovarian, breast and prostate cancers. This book provides insightful views suitable for graduate students, medical students, undergraduate students, basic and clinical scientists, cancer patients as well as the general public.
Editors and Affiliations
Bibliographic Information
Book Title: Hedgehog signaling activation in human cancer and its clinical implications
Editors: Jingwu Xie
DOI: https://doi.org/10.1007/978-1-4419-8435-7
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-4419-8434-0Published: 04 May 2011
Softcover ISBN: 978-1-4899-9541-4Published: 01 October 2014
eBook ISBN: 978-1-4419-8435-7Published: 30 April 2011
Edition Number: 1
Number of Pages: IX, 217
Topics: Cancer Research, Pharmacology/Toxicology