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Journal of Neural Transmission

Translational Neuroscience, Neurology and Preclinical Neurological Studies, Psychiatry and Preclinical Psychiatric Studies

Publishing model:
Hybrid
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Volume 121, Issue 8

August 2014

Special Issue: The fascinating and opposing faces of glutamate in health and disease; A Special Issue on Glutamate in Memory of Prof. Vivian Teichberg

Issue Editors:
  • Mia Levite Teichberg,
  • Peter Riederer
21 articles in this issue

  6. Part 2:

    The role of glutamate and/or of the excitotoxicity mediated by excess glutamate in a kaleidoscope of human diseases, and some therapeutic possibilities for silencing glutamate receptors in such conditions 15 August 2014 Pages: 847 - 847

  21. GLUTAMATE RECEPTOR ANTIBODIES IN NEUROLOGICAL DISEASES: Anti-AMPA-GluR3 antibodies, Anti-NMDA-NR1 antibodies, Anti-NMDA-NR2A/B antibodies, Anti-mGluR1 antibodies or Anti-mGluR5 antibodies are present in subpopulations of patients with either: Epilepsy, Encephalitis, Cerebellar Ataxia, Systemic Lupus Erythematosus (SLE) and Neuropsychiatric SLE, Sjogren’s syndrome, Schizophrenia, Mania or Stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor’s expression, impair glutamate-induced signaling and function, activate Blood Brain Barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and Ataxia in animal models, and can be removed or silenced in some patients by immunotherapy

    • Mia Levite
    Neurology and Preclinical Neurological Studies - Review Article 01 August 2014 Pages: 1029 - 1075

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