1. Design, synthesis, and in vitro evaluation of novel 1,3,4-oxadiazolecarbamothioate derivatives of Rivastigmine as selective inhibitors of BuChE

   • Akram Fallah
   • Farajollah Mohanazadeh
   • Maliheh Safavi

   Original Research 16 December 2019 Pages: 341 - 355

   

2. Discovery of a nanomolar glyoxalase-I inhibitor using integrated ligand-based pharmacophore modeling and molecular docking

   • Nizar A. Al-Shar’i
   • Enas K. Al-Rousan
   • Mohammad A. Hassan

   Original Research 13 December 2019 Pages: 356 - 376

   

3. Styrylcoumarin 7-SC2 induces apoptosis in SW480 human colon adenocarcinoma cells and inhibits azoxymethane-induced aberrant crypt foci formation in BALB/c mice

   • Angie Herrera-R
   • Tonny W. Naranjo
   • Wilson Cardona-G

   Original Research 09 December 2019 Pages: 377 - 395

   

4. Design, synthesis, and bioevaluation of novel oxoindolin-2-one derivatives incorporating 1-benzyl-1H-1,2,3-triazole

   • Ta Thu Lan
   • Duong Tien Anh
   • Nguyen-Hai Nam

   Original Research 25 December 2019 Pages: 396 - 408

   

5. Synthesis, cytotoxicity, and antitubercular studies of novel thiophene containing 2-methyl-3-methyl/ethyl acrylates from Baylis–Hillman adducts

   • Neelaiah Babu G.
   • Abi Tadesse
   • Vijai Basker G.

   Original Research 12 December 2019 Pages: 409 - 416

   

6. Antimycotic sensitivity evaluation against Candida ATCC species of 1,2,3-triazoles derived from 5-chloro-2(2,4-dichlorophenoxy)phenol

   • Cristian A. Pastrana-Gómez
   • Carmen Cecilia Almonacid-Urrego
   • Erick Cuevas-Yáñez

   Original Research 17 December 2019 Pages: 417 - 425

   

7. Hostaflavanol A, a new anti-inflammatory and antioxidant activities flavanol from the flowers of Hosta plantaginea

   • Li Yang
   • Yi-min Lin
   • Jun-wei He

   Original Research 14 December 2019 Pages: 426 - 430

   

8. Synthesis, in vitro antigiardial activity, SAR analysis and docking study of substituted chalcones

   • David Cáceres-Castillo
   • Rubén M. Carballo
   • Gonzalo J. Mena-Rejón

   Original Research 27 December 2019 Pages: 431 - 441

   

9. Design, synthesis and biological evaluation of novel N,4-diphenylthiazol-2-amine derivatives

   • AfraQuasar A. Nadaf
   • Delicia A. Barretto
   • Imtiyaz Ahmed M. Khazi

   Original Research 30 December 2019 Pages: 442 - 458

   

10. Synthesis and biological activity of fibrate-based acyl- and alkyl-phenoxyacetic methyl esters and 1,2-dihydroquinolines

    • Abraham Pucheta
    • Aarón Mendieta
    • Joaquín Tamariz

    Original Research 26 January 2020 Pages: 459 - 478

    

11. Curcumin analogs: synthesis and biological activities

    • Mahmood Khudhayer Oglah
    • Yasser Fakri Mustafa

    Original Research 30 December 2019 Pages: 479 - 486

    

12. Naphthoquinones isolated from Eleutherine plicata herb: in vitro antimalarial activity and molecular modeling to investigate their binding modes

    • Valdicley Vieira Vale
    • Jorddy Neves Cruz
    • Maria Fani Dolabela

    Original Research 18 January 2020 Pages: 487 - 494

    

13. Synthesis, biological activities, and 3D-QSAR studies of (R)-2-phenyl-4,5-dihydrothiazole-4-carboxamide derivatives containing a sulfonohydrazide moiety

    • Jingbo Liu
    • Fengyun Li
    • Zhengming Li

    Original Research 15 January 2020 Pages: 495 - 503

    

14. Binding mechanism, conformation, and stability of diflunisal and mycophenolic acid with p300 HAT enzyme using molecular dynamics simulation and binding free energy analysis

    • Sivanandam Magudeeswaran
    • Kumaradhas Poomani

    Original Research 14 January 2020 Pages: 504 - 518

    

15. A conjugated mTOR/MEK bifunctional inhibitor as potential polypharmacological anticancer agent: the prototype compound discovery

    • Qiangqiang Tao
    • Fang Fang
    • Hao Wang

    Original Research 13 January 2020 Pages: 519 - 527

    

16. Synthesis, anticancer evaluation, and molecular docking studies of benzoxazole linked combretastatin analogues

    • Vukoti Kiran Kumar
    • Venkat Swamy Puli
    • K. R. S. Prasad

    Original Research 18 January 2020 Pages: 528 - 537

    

17. Design, synthesis, and characterization of novel substituted 1,2,4-oxadiazole and their biological broadcast

    • Paranjay H. Parikh
    • Jignesh B. Timaniya
    • Kaushal P. Patel

    Original Research 18 January 2020 Pages: 538 - 548

    

18. Potential neurotrophic activity and cytotoxicity of selected C21 steroidal glycosides from Cynanchum otophyllum

    • Jinrun Dong
    • Grace Gar-Lee Yue
    • Minghua Qiu

    Original Research 17 January 2020 Pages: 549 - 555

    

19. Repositioning of fluoxetine and paroxetine: study of potential antibacterial activity and its combination with ciprofloxacin

    • Vitória S. Foletto
    • Marissa B. Serafin
    • Rosmari Hörner

    Original Research 18 January 2020 Pages: 556 - 563

    

20. Synthesis and evaluation of chromone-2-carboxamido-alkylamines as potent acetylcholinesterase inhibitors

    • Paptawan Suwanhom
    • Teerapat Nualnoi
    • Luelak Lomlim

    Original Research 21 January 2020 Pages: 564 - 574