1. A 50-year perspective of a family with chromosome-14-linked Alzheimer’s disease

   • L. Gustafson
   • Arne Brun
   • Magnus Abrahamson

   Original investigation Pages: 253 - 257

2. Identification of CpG islands hypermethylated in human lung cancer by the arbitrarily primed-PCR method

   • Takashi Kohno
   • Masashi Kawanishi
   • J. Yokota

   Original investigation Pages: 258 - 264

3. Multiple different missense mutations in the pore region of HERG in patients with long QT syndrome

   • C. A. Satler
   • Mark R. Vesely
   • A. H. Beggs

   Original investigation Pages: 265 - 272

4. Linkage of the apo CIII microsatellite with isolated low high-density lipoprotein cholesterol

   • Cecilia M. Devlin
   • Valerie L. Prenger
   • Michael Miller

   Original investigation Pages: 273 - 281

5. Isolation of the human BACH1 transcription regulator gene, which maps to chromosome 21q22.1

   • Jean-Louis Blouin
   • Geneviève Duriaux Saïl
   • S. E. Antonarakis

   Original investigation Pages: 282 - 288

6. Identification and characterization of a new human cDNA from chromosome 21q22.3 encoding a basic nuclear protein

   • Aliana Egeo
   • Michela Mazzocco
   • P. Scartezzini

   Original investigation Pages: 289 - 293

7. Novel mutations of the peripheral myelin protein22 gene in two pedigrees with Dejerine-Sottas disease

   • Tohru Ikegami
   • Hiroyuki Ikeda
   • K. Hayasaka

   Original investiagation Pages: 294 - 298

8. A high risk phenotype of hypertrophic cardiomyopathy associated with a compound genotype of two mutated β-myosin heavy chain genes

   • Brigitte Jeschke
   • Kerstin Uhl
   • H.-P. Vosberg

   Original investigation Pages: 299 - 304

9. Novel and recurrent tyrosine aminotransferase gene mutations in tyrosinemia typeII

   • Regina Hühn
   • Heike Stoermer
   • G. Scherer

   Original investigation Pages: 305 - 313

10. Genetic and immunohistochemical detection of mutations inactivating the keratinocyte transglutaminase in patients with lamellar ichthyosis

    • Hans Christian Hennies
    • Michael Raghunath
    • André Reis

    Original investigation Pages: 314 - 318

11. X chromosome-inactivation patterns in patients with Rett syndrome

    • A. C. Victorino Krepischi
    • Fernando Kok
    • P. Guimarães Otto

    Original investigation Pages: 319 - 321

12. Exclusion of five subunits of cGMP phosphodiesterase in Leber’s congenital amaurosis

    • I. Perrault
    • Sophie Châtelin
    • Josseline Kaplan

    Original investigation Pages: 322 - 326

13. Familial mitochondrial DNA depletion in liver: haplotype analysis of candidate genes

    • Johannes N. Spelbrink
    • Mieke J. M. Van Galen
    • Coby Van den Bogert

    Original investigation Pages: 327 - 331

14. Allele frequencies of hereditary hemochromatosis gene mutations in a local population of west Brittany

    • P. Jézéquel
    • M. Bargain
    • I. Dorval

    Original investigation Pages: 332 - 333

15. Mutation analysis of the dystrophin gene in Southern French DMD or BMD families: from Southern blot to protein truncation test

    • Sylvie Tuffery
    • Sylvie Chambert
    • M. Claustres

    Original investigation Pages: 334 - 342

16. Analysis of low density lipoprotein receptor gene mutations and microsatellite haplotypes in Greek FH heterozygous children: six independent ancestors account for 60% of probands

    • Joanne Traeger-Synodinos
    • Nicholas Mavroidis
    • Nicholas Matsaniotis

    Original investigation Pages: 343 - 347

17. Breast cancer risk assessment: use of complete pedigree information and the effect of misspecified ages at diagnosis of affected relatives

    • Silke Schmidt
    • H. Becher
    • Jenny Chang-Claude

    Original investigation Pages: 348 - 356

18. Variable number tandem repeat polymorphism of the mucin genes located in the complex on 11p15.5

    • Lynne E. Vinall
    • Alexander S. Hill
    • D. M. Swallow

    Original investigation Pages: 357 - 366

19. Two novel mutations in exons 19a and 20 and a BsaI polymorphism in a newly characterized intron of the neurofibromatosis type 1 gene

    • Anja Klose
    • Peter Nicholas Robinson
    • H. Peters

    Original investigation Pages: 367 - 371

20. Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM

    • Xiao-Hong Huang
    • Vappu Rantalaiho
    • T. Lehtimäki

    Original investigation Pages: 372 - 378