1. In this issue

   • Fred Bosman

   Editorial 13 April 2016 Pages: 381 - 381

2. RAS testing in metastatic colorectal cancer: advances in Europe

   • J Han JM Van Krieken
   • Etienne Rouleau
   • Andreas Jung

   Review and Perspectives Open access 16 November 2015 Pages: 383 - 396

3. Tumour budding in colorectal cancer: what do we know and what can we do?

   • Linde De Smedt
   • Sofie Palmans
   • Xavier Sagaert

   Review and Perspectives 27 November 2015 Pages: 397 - 408

   

4. Negative association between GATA3 and fascin could predict relapse-free and overall survival in patients with breast cancer

   • Kyueng-Whan Min
   • Dong-Hoon Kim
   • Kyoung Min Moon

   Original Article 30 December 2015 Pages: 409 - 416

   

5. Application of the 2013 ASCO/CAP guideline and the SISH technique for HER2 testing of breast cancer selects more patients for anti-HER2 treatment

   • António Polónia
   • Dina Leitão
   • Fernando Schmitt

   Original Article 11 January 2016 Pages: 417 - 423

   

6. Prognostic significance of tumor regression in lymph nodes after neoadjuvant therapy for rectal carcinoma

   • M. J. Fernández-Aceñero
   • M. Granja
   • L. Estrada

   Original Article 11 January 2016 Pages: 425 - 430

   

7. A significant subgroup of resectable gallbladder cancer patients has an HER2 positive status

   • Hiroshi Yoshida
   • Kazuaki Shimada
   • Nobuyoshi Hiraoka

   Original Article 13 January 2016 Pages: 431 - 439

   

8. Intrafollicular Epstein-Barr virus-positive large B cell lymphoma. A variant of “germinotropic” lymphoproliferative disorder

   • Luisa Lorenzi
   • Silvia Lonardi
   • Fabio Facchetti

   Original Article 13 January 2016 Pages: 441 - 450

   

9. Doing more with less: fluorescence in situ hybridization and gene sequencing assays can be reliably performed on archival stained tumor tissue sections

   • Giuseppe Pelosi
   • Federica Perrone
   • Ugo Pastorino

   Original Article 27 January 2016 Pages: 451 - 461

   

10. Expression of the CXCR4 ligand SDF-1/CXCL12 is prognostically important for adenocarcinoma and large cell carcinoma of the lung

    • William Sterlacci
    • Shereen Saker
    • Alexandar Tzankov

    Original Article 27 January 2016 Pages: 463 - 471

    

11. Consistency in recognizing microinvasion in breast carcinomas is improved by immunohistochemistry for myoepithelial markers

    • G. Cserni
    • C. A. Wells
    • S. Bianchi

    Original Article 27 January 2016 Pages: 473 - 481

    

12. The zinc-finger transcription factor SALL4 is frequently expressed in human cancers: association with clinical outcome in squamous cell carcinoma but not in adenocarcinoma of the esophagus

    • Ergin Kilic
    • Pierre Tennstedt
    • Waldemar Wilczak

    Original Article 27 January 2016 Pages: 483 - 492

    

13. Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinoma

    • Arvydas Laurinavicius
    • Benoit Plancoulaine
    • Ian O. Ellis

    Original Article 27 January 2016 Pages: 493 - 502

    

14. Funisitis is associated with adverse neonatal outcome in low-risk unselected deliveries at or near term

    • F. A. Jessop
    • C. C. Lees
    • N. J. Sebire

    Original Article Open access 11 February 2016 Pages: 503 - 507